molecular basis of lys11

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molecular basis of lys11

(PDF) Molecular basis of Lys11-polyubiquitin specificity

and reveal the molecular basis of Cezanne s Lys11 specificity (Fig.4d).The dynamic Cez apo state engages polyubiq uitin at the S1 site,releas - ing Cys-loop-mediated auto inhibition.12345NextCited by 79Publish Year 2016Author Tycho E.T.Mevissen,Yogesh Kulathu,Monique P.C.Mulder,Paul P.Geurink,Sarah L.Maslen,Malte GMolecular basis of Lys11-polyubiquitin specificity in the Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne Mevissen,Tycho E.T.; Kulathu,Yogesh; Mulder,Monique P.C.; Geurink,Paul P.; Maslen,Sarah L.; Gersch,Malte Published in Nature DOI 10.1038/nature19836 Publication date 2016 Document Version Peer reviewed version Link to publication in Discovery Research Portal

Cited by 79Publish Year 2016Author Tycho E.T.Mevissen,Yogesh Kulathu,Monique P.C.Mulder,Paul P.Geurink,Sarah L.Maslen,Malte GMolecular basis of Lys11-polyubiquitin specificity in the

Oct 01,2016·Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne - Europe PMC Article - Europe PMC FULL TEXT Abstract The post-translational modification of proteins with polyubiquitin regulates virtually all aspects of cell biology.Eight distinct chain linkage 1Cited by 79Publish Year 2016Author Tycho E.T.Mevissen,Yogesh Kulathu,Monique P.C.Mulder,Paul P.Geurink,Sarah L.Maslen,Malte GMolecular basis of Lys11-polyubiquitin specificity in the Oct 01,2016·Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne Mevissen,Tycho E.T.Cited by 79Publish Year 2016Author Tycho E.T.Mevissen,Yogesh Kulathu,Monique P.C.Mulder,Paul P.Geurink,Sarah L.Maslen,Malte GMolecular basis of Lys11-polyubiquitin specificity in the Oct 12,2016·Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne.Tycho E.T.Mevissen 1,Yogesh Kulathu 1

Cited by 79Publish Year 2016Author Tycho E.T.Mevissen,Yogesh Kulathu,Monique P.C.Mulder,Paul P.Geurink,Sarah L.Maslen,Malte GMolecular basis of Lys11-polyubiquitin specificity in the

Publications Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne The post-translational modification of proteins with polyubiquitin regulatesJohn E Burke - Google ScholarMolecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne TET Mevissen,Y Kulathu,MPC Mulder,PP Geurink,SL Maslen,M Gersch, Nature 538 (7625),402-405 ,2016Molecular basis for specificity of the Met1-linked The structures of OTULIN unbound and bound to Met1-linked diubiquitin revealed the molecular basis for OTULIN's specificity [90,91].In the unbound,apo state,the catalytic histidine,His339,is not orientated for correct deprotonation of the catalytic cysteine (Cys129),but is rather held in an autoinhibited conformation by a non

Molecular basis of Lys11-polyubiquitin specificity in the

Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne .By D Komander,TET Mevissen,K Keusekotten and R WienerY-C Juang,SG Hymowitz,IE Wertz,H Tran,J Jin,JDF Licchesi,JC Christianson,H Hu,K Enesa,A Luong,H Hu,F Pareja,A Bremm,S Moniz,A Bremm,PP Geurink,Molecular basis of Lys11-polyubiquitin specificity in the Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne.Mevissen T.E.,Kulathu Y.,Mulder M.P.,Geurink P.P.,Maslen S.L.,Gersch M.,Elliott P.R.,Burke J.E.,van Tol B.D.,Akutsu M.,El Oualid F.,Kawasaki M.,Freund S.M.,Ovaa H.,Komander D.Molecular basis of Lys11-polyubiquitin specificity in the title = Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne,abstract = The post-translational modification of proteins with polyubiquitin regulates virtually all aspects of cell biology.Eight distinct chain linkage types co-exist in polyubiquitin and are independently regulated in cells.

Msc.Bianca D.M.van Tol - Cell Chemical Biology

I studied Molecular Science and Technology (BSc) and Chemistry (MSc) at the University of Leiden and obtained my MSc degree in June 2016,cum laude.In 2015,I joined the lab of Huib Ovaa at the NKI for my MSc internship where I developed synthetic FRET-based probes to study the activity and specificity of deubiquitinating enzymes.OMIM Entry - * 611748 - OTU DOMAIN-CONTAININGThe deduced protein contains more than 800 amino acids and has an N-terminal TRAF (see TRAF1; 601711 )-binding domain,a putative nuclear localization signal,and aThe Molecular Basis of Ubiquitin-Conjugating Enzymes·Mevissen TET,Kulathu Y,Mulder MPC et al (2016) Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne.Nature 538:402405.

title =Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne,abstract = The post-translational modification of proteins with polyubiquitin regulates virtually all aspects of cell biology.Eight distinct chain linkage types co-exist in polyubiquitin and are independently regulated in cells.Cited by:79Publish Year:2016Molecular basis of Lys11-polyubiquitin specificity in the

Was this helpful?Molecular basis of Lys11-polyubiquitin specificity in the Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne Nature.2016 Oct 20;538(7625):402-405.doi 10.1038/nature19836.Epub 2016 Oct 12.Authors Tycho E T Mevissen 1

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